In yesterday’s post about the association between cataracts and dementia, one of the variables that they solved for was the E4 allele of the apolipoprotein E gene (APOE4). The E4 allele of the apolipoprotein E gene (APOE) has been firmly established as a genetic risk factor for many diseases including cardiovascular diseases and Alzheimer’s disease […]

Read More

A neat study from the August 2021 issue of Investigative Ophthalmology and Visual Science. High-Fat Diet Induces Inflammation of Meibomian Gland by Jinghua Bu et al studied mice that were fed a high-fat diet and how it affected the ocular surface. The giant grain of salt regarding this article is this. mice showed extreme hyperlipidemia […]

Read More

We have all been told for years that smoking can increase risk for developing age-related macular degeneration. The study Association of Smoking, Alcohol Consumption, Blood Pressure, Body Mass Index, and Glycemic Risk Factors With Age-Related Macular Degeneration from the November 2021 issue of JAMA Ophthalmology, shows that there is a correlation between smoking and advanced […]

Read More

I very much enjoyed reading this paper. Lower Cognitive Function in Patients With Functionally and Structurally Severe Glaucoma: The LIGHT Study in the October 2021 edition of Journal of Glaucoma. This quote says it all right here. “This cross-sectional study of 172 patients with glaucoma showed that functional and structural glaucoma damage was significantly associated with […]

Read More

Polypoidal choroidal vasculopathy (PCV) is a subset of exudative AMD. Turns out that PCV patients are less sensitive to anti-VEGF therapies, so it’s very important to make this differentiation early in the diagnosis. Differentiating Exudative Macular Degeneration and Polypoidal Choroidal Vasculopathy Using OCT B-Scan PCV presents with specific U-shaped elevations in the RPE using OCT-B. […]

Read More

Chronic central serous chorioretinopathy (cCSC) is something we run into all the time in practice. Acute CSC resolves without intervention in about 84% of cases within 6 months. What should we do in those that don’t resolve? “However, the disease has a strong tendency to become chronic manifesting in frequent recurrence or persistent subretinal fluid […]

Read More